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作者对17例有典型柯兴氏综合征临床表现的患者作了不同方式的地塞米松抑制试验、甲吡酮试验以及血浆 ACTH 测定等项检查。着重对夜间大剂量地塞米松抑制试验(8mg 晚11时一次口服,测定服药前后上午8时的血浆皮质醇)和经典大剂量地塞米松抑制试验(8mg/日,分4次口服,共2日,测定服药前后24小时尿170HCS)作了分析和比较。结果:夜间大剂量地塞米松抑制试验:13例柯兴氏病中10例抑制阳性,3例为边缘结果(分别抑制35.9%、44.5%、38.9%);3例肾上腺皮质肿
The authors conducted a dexamethasone suppression test, metyrapone test, and plasma ACTH test in 17 patients with clinical manifestations of classical Cushing’s syndrome. Focus on the night of high-dose dexamethasone inhibition test (8mg at 11 o’clock once a day, before and after taking medication measured at 8 am of plasma cortisol) and classic high-dose dexamethasone inhibition test (8mg / day, 4 times orally, a total of 2 Day, before and after determination of urine 24 hours urine 170HCS) were analyzed and compared. Results: At night, high-dose dexamethasone inhibition test was performed in 10 patients with Cushing’s disease in 13 cases and 3 cases with marginal results (35.9%, 44.5% and 38.9%, respectively); 3 cases of adrenal cortex