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目的青光眼为一种不可逆性致盲眼病,青光眼防治的关键在于早期诊断,然而多数青光眼患者早期无任何特异性症状,所以需要重视筛查工作,在人群中进行有效的青光眼筛查是青光眼早期诊断的关键[1]。因为青光眼的视野损害为特异性损害,视野检查为早期诊断提供一定特异性的支持,同时视网膜神经纤维层缺损(retinal nerve fibers layer defect,RNFLD)被认为是青光眼早期诊断的一种可靠的客观依据,有学者认为它要比视野缺损的出现早4～6年,而视盘形态学的研究也成为青光眼早期诊断研究的重点[2,3]。所以考虑二者均在早期原发性开角型青光眼(primary open angle glaucoma,POAG)临床诊断方面占有非常重要的地位。本研究意在比较二者在早期青光眼诊断的敏感性及特异性,对其进行分析评估,着重探讨其对早期青光眼诊断的临床意义。
Purpose Glaucoma is an irreversible cause of blindness. The key to prevention and treatment of glaucoma lies in the early diagnosis. However, most patients with glaucoma do not have any specific symptoms in the early stage. Therefore, screening work should be emphasized. Effective glaucoma screening in the population is the early diagnosis of glaucoma The key [1]. Because glaucoma visual field damage is specific damage, visual field examination provides some specific support for early diagnosis, and retinal nerve fiber layer defect (RNFLD) is considered as a reliable objective evidence of early diagnosis of glaucoma , Some scholars think that it is 4 to 6 years earlier than the visual field defect, and disc morphology research has also become the focus of early diagnosis of glaucoma [2,3]. Therefore, considering both of them plays a very important role in the clinical diagnosis of primary open angle glaucoma (POAG). The purpose of this study is to compare the sensitivity and specificity of the two in the diagnosis of early glaucoma, to analyze and evaluate the clinical significance of the two in the diagnosis of early glaucoma.