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本文报告35例成人癌症患者合并染感,口服磺胺甲基异恶唑(SMZ)-甲氧苄氨嘧啶(TMP)的治疗效果,其中血液系统恶性肿瘤31例,实体肿瘤4例。仅3例以前未经抗菌治疗,另32例系曾用抗菌素(主要为羧苄青霉素和氮基甙族)胃肠道外给药治疗无效者,35例均口服SMZ800毫克和TMP160毫克,每8小时1次,19例有效,总治愈率为54％。最常见的染感为肺炎,19例中9例(47％)有效;败血症5例,4例治愈;软组织感染8例,5例有效;3例尿路感染,1例有效。35例中27例分离出病原菌,主
This article reports the treatment effect of 35 cases of adult cancer patients with combined infection and oral administration of sulfamethoxazole (SMZ) - trimethoprim (TMP), including 31 hematological malignancies and 4 solid tumors. Only three cases had not been previously treated with antimicrobial therapy, and the other 32 cases were previously treated with antibiotics (mainly carbenicillin and azidoside) parenteral administration ineffective, 35 patients were oral SMZ800 mg and TMP160 mg every 8 hours 1 times, 19 cases were effective, the total cure rate was 54%. The most common infection was pneumonia, 9 of 19 (47%) were effective; 5 were sepsis and 4 were cured; 8 were soft tissue infections and 5 were effective; 3 were urinary tract infections and 1 was effective. Among 35 cases, 27 cases were isolated from pathogens,