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糖尿病患者常有胃肠激素分泌异常. 本文报道糖尿病患者血浆胃泌素、胃动素水平的检测结果. 并探讨其与糖尿病患病时间、类型、血糖和肝肾功能的关系.1 对象和方法对照组:30例为本院健康献血员,男24例,女6例,均排除胃肠疾病.糖尿病组:32例为本院住院患者,均符合WHO糖尿病诊断标准,其中男23例,女9例,平均年龄54.3±14.3岁.糖尿病病程< 5年者22例,>5年者10例,I型糖尿病5例,其中4例并发酮症酸中毒,Ⅱ型糖尿病27例,存在肝和/或肾功能不全者15例(其中肝肾功能均不全3例,仅肝功能不全8例,肾功能不全4例),肝肾功能正常者17例,空腹血糖(FBG)>7.8mmol/L者19例,<7.8mmol/L者13例.均于清晨空腹采血测定血浆胃泌素和胃动素.胃泌素放免测定盒由北京中国原子能科学研究院提供,胃动素放免
Diabetic patients often have abnormal secretion of gastrointestinal hormone.This article reports the results of plasma gastrin and motilin levels in diabetic patients and explores its relationship with the duration of diabetes, type, blood glucose and liver and kidney function.1 objects and methods Control group: 30 cases of healthy blood donors in our hospital, 24 males and 6 females, all excluding gastrointestinal diseases.Diabetes: 32 cases of hospitalized patients, are in line with the WHO diagnostic criteria for diabetes, including 23 males and females 9 cases with an average age of 54.3 ± 14.3 years.Among 22 cases of diabetes course <5 years, 10 cases of> 5 years, 5 cases of type I diabetes mellitus, 4 cases were complicated with ketoacidosis, 27 cases of type 2 diabetes mellitus, / Or renal dysfunction in 15 cases (including liver and kidney dysfunction in 3 cases, liver dysfunction in 8 cases, renal insufficiency in 4 cases), normal liver and kidney function in 17 cases, fasting blood glucose (FBG)> 7.8mmol / L 19 cases, <7.8mmol / L in 13 cases were fasting blood in the morning for the determination of plasma gastrin and motilin gastrin radioimmunoassay box provided by the Beijing Institute of Atomic Energy, motilin radioimmunoassay