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13例病区胎儿标本来自地氟病区人工流产胎儿,胎龄6～7月。股骨和其他器官标本进行光镜和酶组织化学观察外,还作了骨样本的SEM—EDXA—XM观察和分析以及骨基质糖醛酸、羟脯氨酸生化组分的测定。病区胎儿成骨活跃,骨组织碱性磷酸酶活性增高,3例胎儿骨外膜下有新骨形成。向时观察到小梁矿化不全,骺板软骨发育异常,骨氟含量增高,可能系氟离子透过胎盘屏障沉积于胎儿骨内所致。
Thirteen cases of fetal ward fetuses from abortion fluoride area abortion fetus, gestational age 6-7 months. Femur and other organs specimens were observed by light microscopy and enzyme histochemistry, but also made a bone sample SEM-EDXA-XM observation and analysis of bone matrix uronic acid, hydroxyproline biochemical components. Fetal active bones in the ward, bone tissue alkaline phosphatase activity increased, 3 cases of new bone formation under the fetal epidural. To observe the trabecular mineralization incomplete, epiphyseal plate cartilage dysplasia, increased bone fluoride content may be fluoride ions through the placental barrier deposition in the fetus due to bone.