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目的了解北京市母乳中人工合成麝香及三氯生的污染水平,初步评价婴儿经母乳喂养的暴露量。方法在北京市崇文、海淀、石景山和通州4区县采集母乳样品65份,采用气相色谱串联质谱法(GC-MS/MS)测定13种人工合成麝香及三氯生含量,内标法定量,应用SPSS软件对检测结果进行统计分析,计算婴儿经哺乳的暴露量。结果母乳中检出佳乐麝香、吐纳麝香、OTNE、西藏麝香等四种人工合成麝香及三氯生,含量在0.6～174.1ng/g lipid范围内,不同区县母乳样品中目标化合物的含量存在差异;婴儿经母乳的摄入量为13.5～3917ng。结论常用的人工合成麝香和三氯生在母乳中普遍检出,值得进一步关注,应加强监测,追溯可能的污染来源。
Objective To understand the levels of synthetic musk and triclosan in breast milk in Beijing and to evaluate the exposure of infants to breastfeeding. Methods 65 breast milk samples were collected from Chongwen, Haidian, Shijingshan and Tongzhou districts in Beijing. The contents of 13 synthetic musk and triclosan were determined by gas chromatography-tandem mass spectrometry (GC-MS / MS) The SPSS software was used to make statistical analysis on the test results to calculate the infant lactation exposure. Results Four synthetic musk and triclosan were detected in breast milk, including musk, thompson, OTNE and Tibetan musk. The contents of target compounds in breast milk were 0.6 ~ 174.1 ng / g lipid. There are differences; infant breast milk intake of 13.5 ~ 3917ng. Conclusions The commonly used synthetic musk and triclosan are commonly detected in breast milk and warrant further attention and should be strengthened to monitor and trace possible sources of contamination.