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人类免疫缺陷病毒(HIV)感染增加了患结核病的危险,并使抗结核治疗效果减低。本文回顾性研究1981～1988年间旧金山患艾兹病(AIDS)和结核病患者132例,探讨伴晚期HIV 感染者结核病的临床病程.诊断结核病时尚未确诊为AIDS 者78例(59%),而同时作出AIDS 诊断者18例(14%),余36例(27%)患结核病期间诊断为AIDS。结核病仅限于肺者50例(35%),限于肺外结核者40例(30%),肺内、外均受累者42例(32%)。7例患者于死后才诊断出结核病,治疗的125例从确诊结核起至少随访20个月。51例治疗期间死亡。
Human immunodeficiency virus (HIV) infection increases the risk of tuberculosis and reduces the effectiveness of anti-TB treatment. This study retrospectively reviewed 132 patients with AIDS and tuberculosis in San Francisco from 1981 to 1988 and explored the clinical course of TB with advanced HIV infection.78 patients (59%) were diagnosed as having not yet been diagnosed with AIDS at the same time Eighteen patients (14%) made AIDS diagnoses and 36 (27%) diagnosed AIDS during tuberculosis. Tuberculosis was limited to lungs in 50 cases (35%), limited to pulmonary tuberculosis in 40 cases (30%), pulmonary involvement were 42 cases (32%). Tuberculosis was diagnosed in 7 patients after they died, and 125 patients were followed up for at least 20 months from diagnosis of tuberculosis. 51 patients died during treatment.