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作者报告了4例喉气管支气管炎和1例支气管炎的小儿在输注双异丙酚后死亡的病例,认为与双异丙酚有关.病例1:既往有上呼吸道感染发作史的2岁零9月女孩,体重12.5kg,因喘鸣加重24h入院,体温38℃,吸气性喘鸣和上气道梗阻的体征,诊断为急性细菌性喉气管支气管炎.在全麻下气管插管吸出脓性分泌物并行人工通气.镇静以静脉点滴双异丙酚(在10%intralipid内含10mg/ml),开始为4.8mg·kg~(-1)·h~(-1).细菌培养为卡他球菌.用羟氨苄青霉素和氟氯西林治疗.WBC为24×10~9/L,N80%,血生化检查和x线胸片正常.第2天体
The authors report 4 cases of laryngotracheal bronchitis and 1 case of bronchitis in children died after infusion of propofol, and propofol related. Case 1: Previous history of upper respiratory tract infection in the 2-year-old zero In September, the girl, weighing 12.5 kg, was diagnosed as acute bacterial laryngotracheal bronchitis because of increased wheezing at admission to hospital for 24 hours, body temperature of 38 ° C., inspiratory wheeze and upper airway obstruction. Purulent discharges were performed in parallel with artificial ventilation and sedation was started intravenously with propofol (10 mg / ml in 10% intralipid) starting at 4.8 mg · kg -1 · h -1 Bacterial culture was Cardacacia with amoxicillin and flucloxacillin treatment .WBC was 24 × 10 ~ 9 / L, N80%, blood biochemical tests and normal chest X-ray. The second body