肥胖是原发性高血压的第一危险因素。肥胖性高血压发病率与日俱增,已经成为一个不容忽视的全球性问题,但其机制尚未完全阐明。本文复习了近年来的相关文献,着重从低血清脂联素、瘦素及瘦素抵抗、胰岛素及胰岛素抵抗、肾素-血管紧张素系统激活4个方面阐述了肥胖性高血压的发生、发展机制。 Obesity is the first risk factor for essential hypertension. The increasing incidence of obesity and hypertension has become a global issue that can not be ignored, but its mechanism has not yet been fully elucidated. This review of the literature in recent years, focusing on low serum adiponectin, leptin and leptin resistance, insulin and insulin resistance, renin - angiotensin system activation in four aspects of the occurrence and development of obesity hypertension mechanism.