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原发性圆锥角膜是一种非炎症性的角膜扩张性疾病,以中央角膜变薄,角膜瘢痕形成、角膜突出和不规则近视散光为特征,严重影响视力。本病多发生于青年人,双眼呈渐进性发病。原发性圆锥角膜的确切病因和发病机制尚不明了,可能是多因素的结果,如遗传学说、胶原学说、基因学说、基质学说、代谢与发育障碍学说等。近年来对圆锥角膜的病因学研究取得了一定的进展。
Primary keratoconus is a non-inflammatory corneal dilatation disease characterized by central corneal thinning, corneal scarring, corneal protrusion, and irregular myopic astigmatism, which seriously affect vision. The disease occurred in young people, his eyes were progressive disease. The exact etiology and pathogenesis of primary keratoconus is unknown, and may be the result of many factors, such as genetics, collagen theory, gene theory, stromal theory, metabolic and developmental disorders and so on. In recent years etiology of keratoconus has made some progress.