喹诺酮类抗菌药是化学合成抗菌药中发展最为迅速的一类,与其他所有抗菌药相仿,其临床适应证涉及临床各科,在治疗各类感染取得良好疗效的同时,也出现了某些病原菌对该类药物耐药性上升的现象。临床无指征的不合理使用是病原菌耐药性增长的重要原因之一。为促进该类药物的临床合 Quinolone antibacterials are the most rapidly developing class of chemical synthetic antibacterials. Similar to all other antibacterials, their clinical indications involve all clinical subjects. While treating various types of infections, good results have been obtained and certain pathogenic bacteria have also emerged Drug resistance of these drugs increased phenomenon. Irrational use of clinical indications is one of the important reasons for the growth of pathogenic bacteria resistance. To promote the clinical combination of these drugs