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重症疟疾患者常不能口服抗疟药,直肠用药是一种替代途径。已有临床试验证明青蒿素或青蒿琥酯栓剂能较好地控制重症疟疾。本文作者就青蒿素栓剂的药物代谢动力学进行了研究。 研究对象是8位来自越南的男性非重症
Patients with severe malaria often can not oral malaria drugs, rectal medication is an alternative way. Clinical trials have shown that artemisinin or artesunate suppositories are better able to control severe malaria. The authors studied the pharmacokinetics of artemisinin suppositories. The study population was 8 non-critically ill men from Vietnam