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目的:观察异舒吉和硝酸甘油治疗不稳定型心绞痛的疗效和安全性。方法:选择不稳定型心绞痛患者160例,随机分为异舒吉组80例和硝酸甘油组80例。两组患者均联合应用阿司匹林、受体阻滞剂、调脂药、极化液等常规治疗。异舒吉组患者给予异舒吉10~20 mg静脉滴注,1次/d;硝酸甘油组给予硝酸甘油5~10 mg静脉滴注,1次/d。两组患者均连续静脉滴注7 d。结果:两组间有效率之比无统计学上的差异。两组不良反应相比差异有统计学意义(P<0.05)。结论:异舒吉对不稳定型心绞痛患者有较好的疗效,不良反应小且轻微,优于硝酸甘油,适合临床广泛应用。
Objective: To observe the efficacy and safety of isoszag and nitroglycerin in the treatment of unstable angina pectoris. Methods: One hundred and sixty patients with unstable angina pectoris were randomly divided into Isogluteth 80 and nitroglycerin 80. Two groups of patients were combined with aspirin, receptor blockers, lipid-lowering drugs, and other routine treatment of polar fluid. Isosorbide group patients given Isotoki 10 ~ 20 mg intravenous infusion, 1 / d; nitroglycerin group given nitroglycerin 5 ~ 10 mg intravenously, 1 time / d. Two groups of patients were continuous intravenous infusion of 7 d. Results: There was no significant difference in the rates of efficacy between the two groups. Adverse reactions between the two groups were statistically significant (P <0.05). Conclusion: Isosorbide has a good curative effect on patients with unstable angina pectoris, the adverse reaction is small and slight, which is better than nitroglycerin, which is suitable for clinical application.