骨髓增生异常综合征(MDS)是多能干细胞异常的克隆性疾病,其病因和发病机理不明。免疫学异常与HDS的发病关系,国内报道尚不多见。本文应用一组抗T淋巴细胞单克隆抗体对35例MDS患者外周血CD_2、CD_4、CD_8细胞进行测定,并检测了患者血清免疫球蛋白含量和淋巴细胞转化率,初步探讨了免疫学异常与MDS发病机理的关系。 Myelodysplastic syndrome (MDS) is an aberrant clonal disease of pluripotent stem cells and its etiology and pathogenesis are unknown. Immunological abnormalities and the incidence of HDS, the domestic reports are rare. In this paper, a group of anti-T lymphocyte monoclonal antibodies in peripheral blood of 35 patients with MDS CD_2, CD_4, CD_8 cells were measured, and the patient’s serum immunoglobulin content and lymphocyte conversion rate, preliminary study of immunological abnormalities and MDS Pathogenesis of the relationship.