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本文利用ＡＢＣ－ＥＬＩＳＡ法检测了９７例ＭＧ病人血清内三种抗体：ＡｃｈＲａｂ、Ｐｒ－Ｍａｂ、ＣＡＥａｂ。结果发现：（１）全身型ＡｃｈＲａｂ、ｐｒ－Ｍａｂ阳性率明显高于眼肌型（Ｐ＜０．０１）；ＡｃｈＲａｂ与Ｐｒ－ＭａｂＰ／Ｎ值呈线性正相关（ｒ＝０．７９７Ｐ＜０．０１）。（２）合并胸腺异常者ＣＡＥａｂ阳性率为８４．２％，明显高于对照组（Ｐ＜０．０１）；此组病人ＡｃｈＲａｂ与ＣＡＥａｂＰ／Ｎ值呈显著正相关，Ｐｒ－Ｍａｂ与ＣＡＥａｂＰ／Ｎ值呈非常显著正相关。（ｒ＝０．５１２和ｒ＝０．５９８Ｐ＜０．０１）。（３）８例病人作了治疗前后抗体检测。激素治疗后或切除异常胸腺后，抗体滴度多数下降或有转阴趋势。
In this paper, ABC-ELISA was used to detect the serum levels of three antibodies in 97 MG patients: AchRab, Pr-Mab and CAEab. The results showed that: (1) The positive rate of AchRab and pr-Mab was significantly higher than that of ocular muscle (P <0.01); AchRab was positively correlated with Pr-MabP / N (r = 0.797P < 01). (2) The positive rate of CAEab in patients with abnormal thymus was 84.2%, which was significantly higher than that in the control group (P <0.01). There was a significant positive correlation between AchRab and CAEabP / N in this group. Pr-Mab and CAEabP / N The value was a very significant positive correlation. (R = 0.512 and r = 0.598P <0.01). (3) Eight patients were tested for antibody before and after treatment. After hormone therapy or removal of abnormal thymus, the majority of antibody titers decreased or negative trend.