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目的:观察二氧化碳激光联合胸腺五肽和异维A酸治疗尖锐湿疣的临床疗效。方法:将尖锐湿疣患者120例随机分为观察组及对照组,各60例。对照组给予二氧化碳激光治疗联合胸腺五肽局部注射,观察组在此基础上加用异维A酸胶丸口服。随访6个月,比较2组患者复发率及治愈率。结果:观察组复发率(15%)显著低于对照组(46.67%),观察组治愈率(85%)显著高于对照组(53.33%)。2组均未出现影响治疗的严重不良反应。结论:对尖锐湿疣患者,在二氧化碳激光治疗基础上联合应用胸腺五肽注射液局部注射以及异维A酸胶丸口服,可显著提高治愈率,降低复发率。
Objective: To observe the clinical effect of carbon dioxide laser combined with thymopentin and isotretinoin in the treatment of condyloma acuminatum. Methods: 120 patients with condyloma acuminatum were randomly divided into observation group and control group, 60 cases each. The control group was given carbon dioxide laser treatment combined with thymopentin local injection, the observation group on the basis of the addition of isotretinoin capsules. The patients were followed up for 6 months. The relapse rate and cure rate of the two groups were compared. Results: The recurrence rate (15%) in observation group was significantly lower than that in control group (46.67%). The cure rate in observation group (85%) was significantly higher than that in control group (53.33%). No serious adverse reactions were found in the two groups. Conclusion: In patients with condyloma acuminatum, local injection of thymopentin injection and isotretinoin capsules orally on the basis of carbon dioxide laser treatment can significantly improve the cure rate and reduce the recurrence rate.