论文部分内容阅读
目的：评价ＭＲＩ引导立体定向术在脑深部肿瘤间质性近距离内放疗（ＩＲＢＴ）中的作用。方法：采用颅外解剖标志在ＭＲＩ引导下行单管插植脑深部肿瘤ＩＲＢＴ治疗７８例。ＭＲＩ用于术前定位、放射剂量的设定与调整。结果：手术安全率为１００％，穿刺道偏差在２ｍｍ以内，５４例（８０％）放疗中行剂量调整，肿瘤内放疗后体积缩小７％～９０％（平均３８％）。结论：ＭＲＩ引导立体定向术在ＩＲＢＴ有重要作用：术前确定理想的穿刺道，内放疗前设定理想的等剂量分布曲线，实现动态ＩＲＢＴ。
Objective: To evaluate the role of MRI guided stereotactic surgery in deep brain tumor with interstitial brachytherapy (IRBT). Methods: Extracranial anatomical landmarks were used to treat 78 patients undergoing single vessel implantation of deep brain tumor with IRBT guided by MRI. MRI for preoperative positioning, radiation dose setting and adjustment. Results: The safety rate of operation was 100%, the deviation of puncture channel was within 2mm, and the dosage of 54 patients (80%) was medium dose. The volume of radiotherapy after radiotherapy was reduced by 7% ~ 90% (average 38%). Conclusion: MRI-guided stereotactic technique plays an important role in IRBT. The ideal puncture channel is determined preoperatively and the ideal isodose curve is set before radiotherapy to achieve dynamic IRBT.