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目的 探讨腔隙性脑梗死患者抑郁状态的特点及其相关因素。方法 用抑郁自评量表 (SDS)测定 96例经CT和MRI证实的腔隙性脑梗死患者的抑郁状态 ,并与对照组比较。根据梗死灶的部位、数量进行病例组中抑郁与非抑郁对照比较。结果 腔隙性脑梗死抑郁发生率为 35 .4 % ;腔隙性脑梗死后抑郁的发生率与腔隙梗死灶的数量密切相关 ;皮质下梗死 ,尤其是多灶性腔隙梗死 ,与其他部位梗死相比 ,更易出现抑郁 ;腔隙性脑梗死患者抑郁症的发生与年龄大小、高血压病程成正相关。结论 抑郁为腔隙性脑梗死患者较为常见的症状 ,其抑郁的产生可能与病灶部位的生物效应有关。
Objective To investigate the characteristics and related factors of depression in patients with lacunar infarction. Methods The depressive state of 96 patients with lacunar infarction confirmed by CT and MRI was measured by self-rating depression scale (SDS), and compared with the control group. According to the infarction site, the number of cases of depression and non-depression control comparison. Results The incidence of depression in lacunar infarction was 35.4%. The incidence of depression after lacunar infarction was closely related to the number of lacunar infarcts. Subcortical infarction, especially multifocal lacunar infarction, was associated with other Depression is more likely to occur in the infarction area than in the infarct area. The incidence of depression in patients with lacunar infarction is positively related to the age and the duration of hypertension. Conclusions Depression is a common symptom in patients with lacunar infarction, and its depression may be related to the biological effects of the lesion site.