论文部分内容阅读
采用流化床技术与喷嘴结合的微型包囊法 ,将 3种双歧杆菌、高效活菌保护剂和双歧促生因子一起作为核心物质 ,包封于无毒囊材中制成耐酸肠溶微囊 (或微球 )。微囊在人工模拟胃液 (pH 1.5～ 2 .0 )中处理 4h ,其中的双歧杆菌活菌数仍保持在 4 4 %以上 ;在人工肠液中处理 12min ,微囊全部崩解释放出活性菌 ,在 37℃下保存 3个月 (相当于常温下 1年以上 ) ,其中的活菌数仍大于 10 9个 /g。有效地解决了胃酸、消化酶和抗生素等对活性双歧杆菌的灭活和产品常温保存期短的问题。
Using fluidized bed technology combined with the nozzle microencapsulation method, the three kinds of bifidobacteria, efficient live bacteria protective agent and bifidobacterium promote growth factor together as the core material, encapsulated in non-toxic capsule made of acid-fast enteric Microcapsules (or microspheres). Microcapsules in artificial simulated gastric fluid (pH 1.5 ~ 2.0) for 4h, in which the viable bifidobacteria remain at 44% or more; in artificial intestinal fluid for 12min, the microcapsules all disintegrated to release the active bacteria, Store at 37 ℃ for 3 months (equivalent to 1 year at room temperature), in which the number of viable cells is still more than 109 / g. Effectively solve the stomach acid, digestive enzymes and antibiotics, such as inactivation of live Bifidobacterium and the problem of short storage temperature at room temperature.