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几年来,我们发现6例患者应用施尔康(中美上海施贵宝制药有限公司生产)15～60天,出现头痛、恶心,停服后症状消失。 施尔康中的维生素C能使血管扩张,维生素的环状结构C_2位上的氧具有负电性,能形成负离子与金属的阳离子结合,生成一种复合物,这种复合物能引起头痛、恶心。Mg~(2+)使血管平滑肌松弛,导致血管扩张,头痛、恶心。I_2可致心动过速、支气管炎、失眠;Zn~(2+)可引起头痛;Cu(++)可引起腹泻; Mn可引起头晕、恶心。维生素A大剂量长期使用,可引起骨痛、颅内压高,而致头痛、恶心、脱发、厌食等症。故不可滥服施尔康、服用时间不宜过长。
Over the past few years, we found that six patients with Shi Erkang (Sino-US Shanghai Squibb Pharmaceutical Co., Ltd. production) 15 to 60 days, a headache, nausea, symptoms disappeared after stopping. The vitamin C in Scirocco causes blood vessels to dilate. The oxygen in the C 2 position of the vitamin ring structure is negatively charged and can form anions that combine with the metal cations to form a complex that can cause headache, nausea . Mg ~ (2+) to relax the vascular smooth muscle, leading to vasodilation, headache, nausea. I_2 can cause tachycardia, bronchitis, insomnia; Zn ~ (2+) can cause headache; Cu (++) can cause diarrhea; Mn can cause dizziness, nausea. Long-term use of high doses of vitamin A, can cause bone pain, intracranial pressure, headache, nausea, hair loss, anorexia embolism. Therefore, you can not abuse Schellkang, taking time should not be too long.