The control effects of agricultural antibiotic 702( ag-antibiotic 702) on rice leaf blast and panicle blast were evaluated in field trials. With ag-antibiotic702 and the two-line early hybrid rice 287 as test materials,different concentrations of ag-antibiotic 702 liquids were sprayed at tillering stage and full heading stage of rice. In leaf blast test,the disease indexes of leaf blast at tillering stage were surveyed at 1 d prior to the first spraying and at 15 d post spraying,respectively.The disease indexes( DI) and the rice yield in panicle blast test was investigated at milky stage. Meanwhile,enzyme activities,including peroxidase( POD),catalase( CAT),superoxide dismutase( SOD),phenylalanine ammonia-lyase( PAL),and polyphenol oxidase( PPO),were measured. Kasugamycin( 45 μg/m L)and deionized water were designed as positive and negative controls. When the concentrations of ag-antibiotic 702 were 15,30 and 45 μg/m L,the control effects against leaf blast were 72. 14%,80. 32% and 85. 22%,respectively; the control effects on panicle blast were 74. 08%,84. 87% and 86. 58%,respectively; and the yield increase rates were 17. 28%,21. 40% and 22. 57%,respectively. So,ag-antibiotic 702,as a new agricultural antibiotic fungicide,could effectively control rice blast by inducing defensive enzymes,and increase rice yield. The results will contribute to further development of ag-antibiotic 702 and its application in rice blast control. The control effects of agricultural antibiotic 702 (ag-antibiotic 702) on rice leaf blast and panicle blast were evaluated in field trials. With ag-antibiotic 702 and the two-line early hybrid rice 287 as test materials, different concentrations of ag-antibiotic 702 liquids were sprayed at tillering stage and full heading stage of rice. In leaf blast test, the disease indexes of leaf blast at tillering stage were surveyed at 1 d prior to the first spraying and at 15 d post spraying, respectively. disease disease indexes DI) and the yield of rice in the panicle blast test was investigated at milky stage. However, enzyme activities including peroxidase (POD), catalase (CAT), superoxide dismutase (SOD), phenylalanine ammonia-lyase When the concentrations of ag-antibiotic 702 were 15, 30 and 45 μg / m L, the control effects against leaf blast (45 μg / m L) and deionized water were designed as positive and negative controls were 72. 14%, 80. 32% and 8 5. 22%, respectively; the control effects on panicle blast were 74. 08%, 84. 87% and 86. 58%, respectively; and the yield increase rates were 17. 28%, 21. 40% and 22. 57 %, respectively. So, ag-antibiotic 702, as a new agricultural antibiotic fungicide, could effectively control rice blast by inducing defensive enzymes, and increase rice yield. The results will contribute to further development of ag-antibiotic 702 and its application in rice blast control.