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抗角蛋白自身抗体（ａｎｔｉｋｅｒａｔｉｎａｕｔｏａｎｔｉｂｏｄｙ，ＡｋａｕｔｏＡｂ）的研究已经历了２０余年的时间，对其特性、意义与疾病的关系等方面的认识都有了长足的进步。随着对ＡｋａｕｔｏＡｂ研究的拓展和深入，特别是现代免疫学和分子生物学技术的迅速发
Antikeratin autoantibodies (anti-keratinau-to-antibody, AkautoAb) research has gone through more than 20 years, its characteristics, the relationship between meaning and disease have made great strides. With the expansion and deepening of AkautoAb research, especially the rapid development of modern immunology and molecular biology techniques