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胰岛素依赖型糖尿病(IDDM)患者中的30～40%伴糖尿病肾病(DN),其进行性病程使DN患者很快发展为终末期肾脏病。尽管,控制原发病可减缓或防止糖尿病患者出现肾脏病变,仍不能阻止DN的进展。限制蛋白的食入和血管紧张素酶抑制剂的应用可减缓慢性肾脏疾病的发展,减少尿中蛋白质或白蛋白的排泄,阻止肾小球滤过率(GFR)的急剧下降。本文旨在观察不同蛋白摄入量对DN患者肾功能的影响。
In 30-40% of patients with insulin-dependent diabetes mellitus (IDDM) with diabetic nephropathy (DN), the progressive course of DN patients rapidly progresses to end-stage renal disease. Although control of the primary disease can slow down or prevent kidney disease in diabetic patients, the progression of DN can not be stopped. The use of restricted protein ingestion and angiotensin-converting enzyme inhibitors slows the development of chronic kidney disease, reduces urinary protein or albumin excretion, and prevents a drastic decrease in glomerular filtration rate (GFR). This article aims to observe the different protein intake on renal function in patients with DN.