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目的:研究抗A组轮状病毒鸡卵黄免疫球蛋白在临床上治疗婴幼儿轮状病毒性肠炎的效果。方法:对1996年下半年临床诊断为秋季腹泻并经粪便ELISA检测为A组轮状病毒抗原阳性的住院患儿218例分组进行研究。结果:实验组总治愈率(91/104)显著高于对照组(71/114)(χ2=1812,P<001)。平均止泻天数实验组(298±141)天,对照组(419±152)天。两组差异有非常显著意义(u=610,P<001)。结论:抗A组轮状病毒鸡卵黄免疫球蛋白的被动免疫保护效果显著。
Objective: To study the effect of anti-group A rotavirus yolk immunoglobulin in the treatment of infantile rotavirus enteritis. Methods: A total of 218 children hospitalized with rotavirus antigen positive in group A were enrolled in this study. Results: The total cure rate in the experimental group (91/104) was significantly higher than that in the control group (71/114) (χ2 = 18.12, P <001). Average diarrhea days in the experimental group (2 98 ± 1 41) days, control group (4 19 ± 1 52 days. There was a significant difference between the two groups (u = 610, P <001). Conclusion: The protective effect of passive immunity against group A rotavirus yolk immunoglobulin is significant.