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目的:探索不同药物治疗恶性胸腔积液的成本一效果比。方法:96例中量以上的恶性胸腔积液患者(男性62例,女性34例,平均年龄为56·8岁)分为3组,胸液引流后分别予博莱霉素、天地欣、沙培林腔内注射治疗,并运用临床经济学的成本一效果分析进行评价。结果:在3种药物治疗方案中,博莱霉素组有效率为56·25%,1个疗程该药物费用为924·80元,有效率每增加1个百分点,成本为16·44元;天地欣组有效率为66·67%,1个疗程该药物费用为1108·00元,有效率每增加1个百分点,成本为16·62元:沙培林组有效率为76·47%,1个疗程该药物费用为2354·12元,有效率每增加1个百分点,成本为30·78元。结论:不同药物适合不同经济状况的患者。
Objective: To explore the cost-effectiveness of different drugs for the treatment of malignant pleural effusion. Methods: Ninety-six patients (62 males and 34 females, with an average age of 56.8 years) with moderate or moderate amount of pleural effusion were divided into 3 groups. After drainage of pleural fluid, bleomycin, Perin injection therapy, and the use of clinical economics cost-effectiveness analysis to evaluate. Results: Among the three drug regimens, the effective rate was 56.25% in the bleomycin group, 924.80 yuan in one course of treatment, and the cost was 16.44 yuan for every 1% increase in the effective rate. The effective rate of World Xin Yan was 66.67%, the cost of this medicine was 1,108.00 yuan for 1 course of treatment, and the cost was 16.62 yuan for every 1% increase of effective rate: the effective rate of Sha Pailin was 76.47% 1 course of the drug costs 2354.12 yuan, an increase of 1 percentage point for efficiency, cost 30.78 yuan. Conclusion: Different drugs are suitable for different economic conditions in patients.