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目的本文报告了我院自1999年6月开始应用新型抗癫痫要妥泰治疗儿童癫痫120例,其中男性68例,女性52例。年龄2至12岁,平均年龄5.6岁,病程二个月至10年。其中简单部分发作20例,控制发作12例,显效4例,总有效率100%。复杂部分性发作32例,控制发作12例,显效4例,有效8例,效果差8例,总有效率75%。强直阵挛性发作24例,控制发作8例,显效4例,有效8例,效果差4例,总有效率83.3%。肌阵挛发作24例,显效8例,有效8例,效果差8例,总有效率66.7%。不典型失神发作20例,有效8例,效果差12例,总有效率40%。完全控制发作32例占26.7%显效20例占16.7%,有效36例占30%,效果差32例,总有效率73.3%。简单部分性发作控制好,其次是强直发作和复杂部分性发作,肌阵挛发作较难控制,不典型失神发作及病程长的有合并症的难以控制。本文观察到50%在用药1-3周出现不良反应。说明此不良反应发生在加量期,为可以耐受的一过性不良反应,随着服药时间的延续,不良反应逐渐改善。
Objective This article reports our hospital since June 1999, the application of new antiepileptic Toitai treatment of 120 children with epilepsy, 68 males and 52 females. Aged 2 to 12 years old, with an average age of 5.6 years, duration of two months to 10 years. Of which 20 cases of simple attack, control attack in 12 cases, 4 cases markedly effective, the total effective rate of 100%. Complex partial seizures in 32 cases, control of attack in 12 cases, 4 cases markedly effective in 8 cases, the poor results in 8 cases, the total effective rate of 75%. Twenty-four had tonic-clonic seizures, 8 had seizures, 4 had markedly effective, 8 had an effective result, and 4 had a poor response with a total effective rate of 83.3%. Myoclonic seizures in 24 cases, 8 cases markedly effective in 8 cases, the poor in 8 cases, the total effective rate was 66.7%. 20 cases of atypical absence absence, effective in 8 cases, poor results in 12 cases, the total efficiency of 40%. 32 cases of complete control of attack accounted for 26.7% of 20 cases markedly effective 16.7%, effective 36 cases accounted for 30%, poor results in 32 cases, the total effective rate 73.3%. Simple partial seizure control, followed by tonic seizures and complex partial seizures, myoclonic seizures more difficult to control, atypical seizures and longer duration of complications difficult to control. This article observed 50% adverse reactions in 1-3 weeks of medication. Description of this adverse reaction occurs in the amount of period, as a tolerable transient adverse reactions, with the continuation of medication time, adverse reactions gradually improved.