本文对79例食管静脉曲张的患者应用99.5%纯酒精或50%酒精作硬化治疗的病例进行疗效和安全性的比较。全部病例均有中等至大量出血史,无消化性溃疡和糜烂性粘膜病变。纯酒精治疗组(39例)分成每3周及每周治疗1次的两组;50%酒精治疗组(40例)每3周治疗1次,分成血管内和血管旁注射的两组。注射剂量以在注射点周围出现2.5～1.0cm范围白色区为度。凡每次注射后至下次注射前又有静脉曲张出血,并需输血者定为出血复发。结果:经纯酒精与50%酒精治疗者的平均静脉曲张消失时间分别为14.3±4.6和20.1±6.4周(P<0.05);平均应用硬化剂治 This article 79 cases of esophageal varices in patients with 99.5% pure alcohol or 50% alcohol for sclerotherapy in the case of efficacy and safety comparison. All cases were moderate to massive bleeding history, no peptic ulcer and erosive mucosal lesions. The patients in the pure alcohol group (39 cases) were divided into two groups (every 3 weeks and once a week). The patients in the 50% alcohol group (40 cases) were treated once every 3 weeks and divided into two groups. The injection dose is such that a white area in the range of 2.5 to 1.0 cm appears around the injection point. Where after each injection to the next injection of varicose veins bleeding, and blood transfusion as bleeding recurrence. Results: The average disappearance time of varicose veins by pure alcohol and 50% alcohol were 14.3 ± 4.6 and 20.1 ± 6.4 weeks, respectively (P <0.05). On average, sclerotherapy