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氟苯桂嗪(Flunarizine)是脑益嗪(cinnarizine)的二氟衍生物,其基本药理特性是颌抗细胞外钙质进入细胞内,而细胞内钙与兴奋—反应的生理联接有关。氟苯桂嗪通过抑制钙离子进入前庭壶腹嵴细胞,可减少前庭刺激,治疗迷路性眩晕;通过阻抑钙通路,还可在缺氧时保护脑部,使之免受过量钙离子的刺激,从而可治疗脑血管性眩晕。脑益嗪对眩晕的疗效是已经肯定了的,氟苯桂嗪的作用较脑益嗪更强,也更持久。对动物(家兔)及人类的实验室研究证
Flunarizine is a difluoro derivative of cinnarizine whose basic pharmacological properties are that of anti-extracellular calcium in the jaw, and intracellular calcium is involved in the physiological link of excitation-response. Fluorobenzine inhibits the vestibular stimulation of the vestibule by inhibiting calcium ions into the vestibular cells to treat stunned dizziness and protects the brain from hypoxia by inhibiting the calcium pathway , Which can treat cerebral vascular vertigo. Cerebral Yizhi on the efficacy of vertigo is already affirmed, the role of fluorouracil than the brain Yizheng stronger, but also more durable. Laboratory studies on animals (rabbits) and humans