论文部分内容阅读
目的探讨癫痫患者智能状况、事件相关电位P300(ERPP300)的特点及ERPP300对癫痫患者智能状况的评定价值。方法对40例癫痫患者进行智商及ERPP300测定。结果40例癫痫患者中总智商FIQ≤89者14例,占35%;P300异常者16例,占40%。癫痫智能障碍组的VIQ、PIQ、FIQ、P300PL分别与智能正常组及正常对照组比较,均具有显著性差异(P<0.01)。且癫痫患者P300PL与VIQ、PIQ、FIQ呈负相关。结论癫痫患者易发生智能损害,且智能损害无选择性。智力量表和ERPP300二种检测方法对评判癫痫患者智能障碍具有良好的一致性,而ERPP300能更早期、更客观、快捷、准确地评价癫痫患者智能状况。
Objective To investigate the characteristics of intelligence status, event-related potentials (P300) of epilepsy patients (ERPP300) and the evaluation value of ERPP300 on intelligence status of patients with epilepsy. Methods 40 cases of epilepsy patients were measured by IQ and ERPP300. Results Among 40 epilepsy patients, there were 14 cases with FIQ≤89, accounting for 35%; 16 cases with P300 abnormalities accounting for 40%. VIQ, PIQ, FIQ and P300PL in epilepsy group were significantly different from those in normal group and control group (P <0.01). P300PL was negatively correlated with VIQ, PIQ and FIQ in patients with epilepsy. Conclusion Epilepsy patients prone to intellectual damage, and no selective damage to intelligence. Intelligence scale and ERPP300 two kinds of detection methods for the evaluation of intellectual disabilities in patients with epilepsy has a good consistency, and ERPP300 more early, more objective, quick and accurate evaluation of intelligence in patients with epilepsy.