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目的:探讨孕妇巨细胞病毒(CMV)的感染是否受乙型肝炎病毒的影响以及乙型肝炎孕妇CMV的感染方式。方法:采用ELISA法检测342例乙型肝炎孕妇和484例非乙型肝炎孕妇CMV-IgG、CMV-IgM。对于CMV-IgM阳性血清采用倍比稀释法检测CMV-IgG的滴度,3周后抽血复检CMV-IgM,同时采用倍比稀释法检测CMV-IgG的滴度,并与之前的滴度进行比较。结果:乙型肝炎孕妇组与非乙型肝炎孕妇组的CMV-IgG、CMV-IgM阳性率相近,差异无统计学意义(P>0.05)。乙型肝炎孕妇组的复发感染率明显高于非乙型肝炎孕妇组,差异有统计学意义(P<0.05)。结论:孕妇CMV的感染不受乙型肝炎病毒的影响,乙型肝炎孕妇CMV的感染以复发感染为主。
Objective: To investigate whether the infection of pregnant women with cytomegalovirus (CMV) is affected by Hepatitis B virus and the infection of CMV in pregnant women with Hepatitis B. Methods: CMV-IgG and CMV-IgM were detected in 342 pregnant women and 484 non-HBV pregnant women by ELISA. For CMV-IgM positive sera, the titer of CMV-IgG was detected by fold dilution method. CMV-IgM was withdrawn after 3 weeks, and the titer of CMV-IgG was detected by fold dilution method. Compare. Results: The positive rates of CMV-IgG and CMV-IgM in pregnant women with hepatitis B and non-hepatitis B pregnant women were similar, with no significant difference (P> 0.05). The recurrent infection rate of hepatitis B pregnant women group was significantly higher than that of non-hepatitis B pregnant women group, the difference was statistically significant (P <0.05). Conclusion: The infection of CMV in pregnant women is not affected by hepatitis B virus, and the infection of CMV in pregnant women with hepatitis B is mainly recurrent infection.