论文部分内容阅读
中毒性休克综合征的死亡率为7～10%。一向认为金黄色葡萄球菌是本病最可能的病原菌。据 Alte-meier 等以往的研究发现:每隔4～6年出现不同噬菌体型的金黄色葡萄球菌,以致引起外科和其他医原性感染的流行。中毒性休克综合征的病原菌也有类似现象。因此要考虑有无新的菌株或老的菌株变异,使产生新的毒素而引起中毒性休克综合征。为此,作者从159例中毒性休克综合征病人(实验组)和86例非中毒性休克综合征病人(对照组)(如感染伤口、正常阴道、鼻腔)分离出来的金黄色葡萄球菌,以双盲法进行了细菌的噬菌体分型、Schlievert 毒素试验和抗菌素敏感—耐药性试验。
The mortality rate of toxic shock syndrome is 7 ~ 10%. Staphylococcus aureus has always been considered to be the most probable pathogen of this disease. According to previous studies by Alte-Meier et al., It has been found that different bacteriophage-type Staphylococcus aureus occur every 4 to 6 years, causing the spread of surgical and other iatrogenic infections. Pathogens of toxic shock syndrome also have a similar phenomenon. Therefore, to consider whether there is a new strain or mutation of the old strains, so that the production of new toxins and cause toxic shock syndrome. To this end, the authors isolated S. aureus from 159 patients with toxic shock syndrome (experimental group) and 86 patients with non-toxic shock syndrome (control group) (eg infected wounds, normal vagina, nasal cavity) Double-blinded bacterial phage typing, Schlievert toxin test, and antibiotic susceptibility-resistance test.