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目的探讨治疗生殖道支原体感染和减少复发的有效方法。方法对确诊的生殖道支原体患者随机分为两组,联合用药组60例,口服阿奇霉素和免疫增强剂匹多莫德治疗。对照组60例仅口服阿奇霉素,剂量和疗程与观察组相同。观察疗效及不良反应,并进行统计学分析。结果联合用药组转阴53例,转阴率为88.3%;对照组转阴42例,转阴率为70.0%,两组比较有显著性差异(P<0.05)。分泌物增多、外阴瘙痒、下腹坠胀、泌尿系感染等临床症状的改善情况,两组比较有显著性差异(P<0.05)。两组患者随访1、2、3个月,联合用药组复发率明显低于对照组(P<0.05)。结论阿奇霉素联合匹多莫德片治疗生殖道支原体感染,临床疗效好,复发率低,较单用阿奇霉素具有优越性。
Objective To explore effective methods of treating genital mycoplasma infection and reducing relapse. Methods The patients diagnosed as Mycoplasma genitalium were randomly divided into two groups, 60 cases in combination group and oral azithromycin and Pimientodone, an immunopotentiator. The control group, 60 cases of oral azithromycin only, the same dose and course of treatment with the observation group. Observation of efficacy and adverse reactions, and statistical analysis. Results In the combination group, 53 cases were negative and the negative conversion rate was 88.3%. In the control group, 42 cases were negative and the negative conversion rate was 70.0%. There was significant difference between the two groups (P <0.05). Secretions increased, genital itching, abdominal bulge, urinary tract infection and other clinical symptoms improved, the two groups were significantly different (P <0.05). The two groups were followed up for 1, 2 and 3 months. The relapse rate in combination group was significantly lower than that in control group (P <0.05). Conclusion Azithromycin combined with pidotimod tablets treatment of genital Mycoplasma infection, clinical efficacy, low recurrence rate, compared with azithromycin single superiority.