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目的观察更昔洛韦与干扰素联合治疗儿童病毒性脑膜炎的效果。方法将商丘市妇幼保健院2006年4月至2011年2月收治的43例病毒性脑膜炎患儿随机分为2组即治疗组和对照组,对照组患儿服用更昔洛韦,对照组采用利巴韦林加干扰素联合治疗。结果治疗组总有效率,显著高于对照组的,差异有统计学意义。结论采用更昔洛韦与干扰素联合治疗儿童病毒学脑膜炎安全可靠,不良反应少,值得临床推广应用。
Objective To observe the effect of ganciclovir combined with interferon on children with viral meningitis. Methods 43 cases of viral meningitis in Shangqiu MCH hospital from April 2006 to February 2011 were randomly divided into two groups: treatment group and control group. The control group took ganciclovir and control group Ribavirin plus interferon combination therapy. Results The total effective rate of the treatment group was significantly higher than that of the control group, the difference was statistically significant. Conclusion The combination of ganciclovir and interferon in the treatment of children with virological meningitis is safe and reliable with few adverse reactions. It is worthy of clinical application.