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目的探讨二甲基乙酰胺对职业暴露人群肝肾损害是否存在性别差异。方法现场检测确定二甲基乙酰胺浓度;健康检查男119人,女96人,确定肝肾损害人数。用SPSS11.0软件包,采用χ2检验进行统计学分析。结果现场检测发现有18个检测点(岗位)的二甲基乙酰胺接触浓度超过国家卫生标准,超标点(岗位)数占85.7%;体检结果发现二甲基乙酰胺职业暴露者男女肝功能异常者分别为19.33%和1.04%,而肾功能异常者分别为8.4%和36.46%。不同性别的肝肾损害,差异有统计学意义(P<0.01)。结论二甲基乙酰胺对男性主要为肝功能损伤,女性主要为肾功能损伤。
Objective To investigate the gender difference of dimethylacetamide on occupationally exposed liver and kidney damage. Methods The concentration of dimethylacetamide was determined by on-site test. 119 males and 96 females were examined healthily to determine the number of liver and kidney damage. SPSS11.0 software package, using χ2 test for statistical analysis. Results On-site test found that the contact concentration of dimethylacetamide at 18 test sites (post) exceeded the national health standards, the number of exceeding the standard (post) accounted for 85.7%; physical examination found that men and women with occupational exposure to dimethylacetamide had abnormal liver function 19.33% and 1.04% respectively, while those with abnormal renal function were 8.4% and 36.46% respectively. Different gender of liver and kidney damage, the difference was statistically significant (P <0.01). Conclusion Dimethylacetamide is mainly for liver injury in males, but mainly for renal dysfunction in females.