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目的分析老年肢端肥大症合并阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的临床特点、可能的发生机制,以及治疗方法,为临床提供理论依据和指导。方法总结近期收治的4例老年性肢端肥大症合并OSAHS患者的临床资料,分析患者接受持续气道正压通气(CPAP)呼吸机治疗的临床特征。结果患者存在重度OSAHS合并夜间重度低氧血症,并患有高血压和糖尿病;存在垂体内分泌变化。CPAP呼吸机对患者OSAHS治疗有益。结论临床肢端肥大症并发OSAHS较常见,老年人更易合并严重的睡眠呼吸暂停,患者有必要行多导睡眠图监测。CPAP可使OSAHS患者的临床症状得到缓解和改善。
Objective To analyze the clinical features, possible mechanism and treatment of elderly patients with acromegaly and obstructive sleep apnea-hypopnea syndrome (OSAHS), and to provide theoretical basis and guidance for clinical practice. Methods The clinical data of 4 recent cases of senile acromegaly with OSAHS admitted to our hospital were analyzed. The clinical characteristics of patients undergoing continuous positive airway pressure (CPAP) ventilator were analyzed. Results The patient had severe OSAHS with nocturnal hypoxemia and had hypertension and diabetes mellitus; there was a change in pituitary endocrine. CPAP ventilator benefits patients with OSAHS. Conclusions Clinical acromegaly complicated with OSAHS is more common. Older adults are more likely to have severe sleep apnea, and it is necessary for them to monitor polysomnography. CPAP can relieve and improve the clinical symptoms of OSAHS patients.