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(S)-(+)-Ipalbidine,[a]_D~25+54.1°(c=1,ethanol)as hydrobromide,was synthesizedfrom natural(S)-proline with retention of configuration.The hydrobromide of the synthetic productwas identical in all respects with that of the optically active natural ipalbidine isolated from theChinese species Ipomoea hardwickii Hemsl.
(S) - (+) - Ipalbidine, [a] _D ~ 25 + 54.1 ° (c = 1, ethanol) as hydrobromide, waswasfromfrom natural (S) -proline with retention of configuration.The hydrobromide of the synthetic product was identical in all respects with that of the optically active natural ipalbidine isolated from theChinese species Ipomoea hardwickii Hemsl.