糖皮质激素在许多疾病的化学治疗中起有主要作用,尤其在有炎症及/或免疫参与的疾病中起着主要的病理生理作用。虽然已经知道许多关于糖皮质激素的亚细胞及组织效应,但对于它们抗炎症和免疫抑制效应的确切作用机理,以及这些效应与疾病控制之间的关系,则仍未阐明。本文着重讨论糖皮质激素对血循环中各白细胞群的效应,以及在非 Glucocorticoids play a major role in the chemotherapeutic treatment of many diseases, and in particular play a major pathophysiological role in diseases with inflammatory and / or immune involvement. Although much is known about subcellular and tissue effects of glucocorticoids, the exact mechanism of their anti-inflammatory and immunosuppressive effects and the relationship between these effects and disease control are not yet elucidated. This article focuses on the effect of glucocorticoids on the various white blood cell populations in the blood circulation, as well as in the non-