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目的比较维吾尔族和汉族2型糖尿病住院患者颈动脉粥样硬化的检出率及相关的危险因素。方法136例维吾尔族和158例汉族2型糖尿病住院患者进行颈动脉B超检查,记录临床资料,测量收缩压(SBP)、舒张压(DBP)、计算体质指数(BMI),检测糖化血红蛋白(HbA1C)、总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、脂蛋白a(LP(a))、凝血酶原时间(PT)、活化部分凝血酶原时间(APTT)、凝血酶时间(TT)、纤维蛋白原(Fg)。结果维吾尔族和汉族2型糖尿病患者颈动脉粥样硬化检出率分别为38.2%,51.8%,维吾尔族患者高于汉族(P<0.05)。维吾尔族患者BMI、LDL-C和病程分别为(28.67±3.02)kg/m2(、3.29±0.53)mmol/L(、5.42±0.58)a,BMI、LDL-C高于汉族患者,差别有统计学意义(P<0.05),而病程明显短于汉族患者(P<0.05)。结论维吾尔族2型糖尿病住院患者颈动脉粥样硬化的检出率显著高于汉族患者并有早发倾向,这可能与维吾尔族患者的BMI和LDL-C水平高于汉族患者有关。
Objective To compare the prevalence of carotid atherosclerosis and related risk factors among inpatients with Uygur and Han type 2 diabetes mellitus. Methods 136 cases of Uygur and 158 Han patients with type 2 diabetes mellitus underwent carotid artery ultrasound examination. The clinical data were recorded. SBP and DBP were measured. Body mass index (BMI), HbA1C (TC), triglyceride (TG), HDL-C, LDL-C, LP (a), prothrombin Time (PT), activated partial prothrombin time (APTT), thrombin time (TT), fibrinogen (Fg). Results The prevalence of carotid atherosclerosis in Uygur and Han patients with type 2 diabetes mellitus were 38.2% and 51.8%, respectively, and higher in Uigur patients than in Han people (P <0.05). The duration of BMI and LDL-C in Uygur patients were (28.67 ± 3.02) mmol / L (5.42 ± 0.58) a, and the BMI and LDL-C were higher than those in Han patients (P <0.05), while the course of disease was significantly shorter than that of Han patients (P <0.05). Conclusions The prevalence of carotid atherosclerosis in Uighur type 2 diabetes inpatients is significantly higher than that in Han patients and has a tendency of premature onset. This may be related to the higher level of BMI and LDL-C in Uygur patients than in Han patients.