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肝豆状核变性(Wilson氏病)是一种常染色体隐性遗传性疾病,是由于铜代谢异常而蓄积于体内,造成组织器官损害。以往本病预后不良。近20年来,随着治疗方法的进展,预后发生了很大变化。近年来,国外用锌盐治疗本病,收效迅速且无不良反应,被认为是一种有希望的治疗方法。现就锌治疗本病的有关问题综述如下。本病抑铜治疗包括减少铜的吸收和驱除组织内过量积存的铜两方面。减少铜吸收的措施有限制铜的摄入(每日不超过2mg)和口服硫化钾或阳离子交换树脂,这些药物在
Wilson’s disease (Wilson & apos; s disease) is an autosomal recessive disease that accumulates in the body due to abnormal copper metabolism and causes tissue and organ damage. In the past the prognosis of this disease is not good. The past 20 years, with the progress of treatment, the prognosis has undergone great changes. In recent years, the treatment of this disease with zinc abroad, with rapid success and no adverse reactions, is considered a promising treatment. Now on the zinc treatment of the disease related issues are summarized below. Copper suppression of this disease includes the reduction of copper absorption and removal of excessive accumulation of copper within the organization of the two aspects. Measures to reduce copper absorption limit copper intake (no more than 2 mg daily) and oral potassium sulphate or cation exchange resins at