【摘 要】
:
脑脓肿是具有致命风险的中枢神经系统感染性疾病,及时有效的治疗脑脓肿依赖于神经内科、神经影像科和神经外科的积极合作.神经影像技术指导下的神经外科手术不仅可以切除病灶,还可以为病原菌诊断提供有效帮助.在经验性抗感染治疗过程中,要充分考虑厌氧菌感染的可能性.经足够疗程静脉抗生素治疗的患者,可以给予适宜的口服抗生素治疗,并在门诊随诊过程中,关注患者病灶变化及癫痫等常见并发症的发生.综上,本文对脑脓肿诊断及治疗新进展进行综述.
【机 构】
:
100070 首都医科大学附属北京天坛医院神经病学中心神经感染与免疫科
论文部分内容阅读
脑脓肿是具有致命风险的中枢神经系统感染性疾病,及时有效的治疗脑脓肿依赖于神经内科、神经影像科和神经外科的积极合作.神经影像技术指导下的神经外科手术不仅可以切除病灶,还可以为病原菌诊断提供有效帮助.在经验性抗感染治疗过程中,要充分考虑厌氧菌感染的可能性.经足够疗程静脉抗生素治疗的患者,可以给予适宜的口服抗生素治疗,并在门诊随诊过程中,关注患者病灶变化及癫痫等常见并发症的发生.综上,本文对脑脓肿诊断及治疗新进展进行综述.
其他文献
The neuromuscular junction (NMJ) is the peripheral synapse controlling muscle contraction and coordinated movement in a wide variety of animals. In humans, the mature NMJ is the primary target of morphological disassembly and functional decline in several
1病例报告 患者女,65岁.“意识障碍、发热1 d余”于2019-9-4入院.患者9月3日出现口吐白沫,意识模糊,但呼之可应,有小便失禁,无肢体抽搐,遂送至当地医院就诊,行头部CT检查未见脑出血,最高体温达39.5℃.考虑“脑血管意外”,给予营养神经、护胃、补液、降温等处理后症状未见缓解,当天20点左右患者意识障碍加重,呼之不应,遂转至作者医院就诊.
阿尔茨海默病(Alzheimer disease,AD)是一种起病隐匿,呈进行性发展的神经系统退行性疾病.近些年,越来越多的研究发现类淋巴系统与AD中的异常蛋白清除障碍密切相关.本文总体阐述了类淋巴系统的发现及其与AD的关系,重点对其对脑内β-淀粉样蛋白(amyloid-beta protein,Aβ)、tau蛋白的清除功能及影响因素,以及基于类淋巴系统机制治疗AD的最新研究成果进行综述.
1病例报告 患者男性,55岁,主因脑出血术后6个月于2019-05-30入院.患者于本次入院6个月前情绪激动后出现手麻,随即意识丧失,就诊于当地医院查头颅CT示脑干出血,行去骨瓣减压术,因左眼睑闭合不全导致暴露性角膜炎行左睑缝合术,现遗留意识障碍,四肢活动障碍就诊于作者科室.
Brain injury-induced neurological deficits typically develop on the contralateral side of the body and include abnormal posture, motor weakness, and spasticity. It is believed that the interruption of descending neural pathways that convey supraspinal com
Within the last several decades, the scientific community has made substantial progress in elucidating the complex pathophysiology underlying spinal cord injury. However, despite the many advances using conventional mammalian models, both cellular and axo
Valuable implement to the animal neurological models: Neurological diseases remain the largest cause of death and disability. The discovery of effective therapies is chiefly hindered by the lack of realistic neurological models. Unlike other tissues, it i
Recent emerging research on intestinal microbiota and its contribution to the central nervous system during health and disease has attracted significant attention. Age-related intestinal microbiota changes initiate brain aging and age-related neurodegener
呋喃唑酮(furazolidone),又名痢特灵,是硝基呋喃类抗菌药,为广谱杀菌剂,临床主要用于治疗肠道细菌感染和根除幽门螺杆菌,有较大处方量.现将1例长期服用呋喃唑酮致中毒性脑病及周围神经病患者的临床表现及影像特征进行报道,加强对其不良反应的认识.
Although there is ample evidence that central nervous system progenitor pools respond to traumatic brain injury, the reported effects are variable and likely contribute to both recovery as well as pathophysiology. Through a better understanding of the div