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前列腺素(PG)的研究进展很快,已成为一个由多种重要内源性生理活性物质组成的大家庭。不少医学分支对PG、血凝素(TX)以及前列环素(PGI_2)的生理活性、生物合成、拮抗剂或合成酶抑制剂等产生浓厚兴趣;对血小板聚集及冠心病、发热、炎症、分娩及流产、致癌物等提出新见解,为设计新药提供重要线索。国内在PG应用研究方面,如平喘,鼻炎及动脉粥样硬化的治疗,促进家畜发情、排卵及提高受孕率,治疗母牛持久黄体不育症及终止早、中期妊娠等已取得不少进展。
Research on prostaglandin (PG) has progressed rapidly and has become a family of many important endogenous physiologically active substances. Many medical branches have a great interest in the physiological activity, biosynthesis, antagonist or synthetase inhibitors of PG, hemagglutinin (TX) and prostacyclin (PGI_2), and have a great interest in platelet aggregation and coronary heart disease, fever, inflammation, Childbirth and abortion, carcinogens and other new ideas, to provide important clues to the design of new drugs. Domestic PG application research, such as asthma, rhinitis and atherosclerosis treatment, and promote livestock estrus, ovulation and pregnancy rate, long-term treatment of cows luteal infertility and termination of early and mid-term pregnancy have made much progress .