论文部分内容阅读
测得86例心衰小儿血清地高辛浓度治疗范围(1.9±0.61)μg/L,不同年龄组的治疗浓度无明显差异。20例口服与静脉给药对比,当静脉给药剂量为口服给药的2/3时,前者的血药浓度明显高于后者。血药浓度≥2μg/L时,地高辛中毒的发生率明显增加,且均为心肌疾病患儿。治疗过程中出现心律紊乱或消化道症状不能肯定为地高辛中毒。
86 cases of children with heart failure serum digoxin concentration treatment range (1.9 ± 0.61) μg / L, the treatment of different age groups no significant difference. 20 cases of oral administration and intravenous contrast, when the intravenous dose of oral administration of 2/3, the former plasma concentration was significantly higher than the latter. Blood concentration ≥ 2μg / L, the incidence of digoxin poisoning increased significantly, and are children with myocardial disease. Heart failure during treatment or gastrointestinal symptoms can not be sure for digoxin poisoning.