结肠黑变病(melanosis coli)临床少见,我院自1985年10月以来,经纤维结肠镜及病理检查证实4例,现报告如下。病历摘要例1:男,69岁。便秘10余年,伴左下腹隐痛,常服用藩泻叶、大黄,果导等。查体左下腹有压痛。1985年10月内镜示横结肠、降结肠粘膜呈细网状花 Colon melanosis (melanosis coli) clinical rare, our hospital since October 1985, confirmed by fibro-colonoscopy and pathology in 4 cases, are as follows. Case history summary 1: Male, 69 years old. Constipation for more than 10 years, with pain in the lower abdomen, often taking vampire leaves, rhubarb, fruit guide and so on. Physical examination left lower quadrant tenderness. In October 1985 endoscopic transverse colon, descending colon mucosa was fine mesh flowers