论文部分内容阅读
一、癌瘤化疗的分子生物学原理癌瘤细胞的生长、分裂、繁殖完全依赖于癌瘤细胞内的核酸代谢和蛋白质的合成。瘤细胞是人体内一种变异细胞,它具有三个特点:(1)不断地增殖而不受宿主的控制;(2)形态不成熟而功能完整;(3)具有明显地浸润性和转移性。从理论推算,瘤细胞是按指数方式增殖的,从一个瘤细胞发展到1厘米~3大小、约1克的瘤块,即10~9个细胞,要经过30代的增殖周期,再增大至1公斤左右瘤块,即10~(12)个
First, the principle of molecular biology of cancer chemotherapy The growth, division, and reproduction of cancer cells depend entirely on the metabolism of nucleic acids and protein synthesis in cancer cells. A tumor cell is a variant cell in the human body. It has three characteristics: (1) it continuously proliferates without being controlled by the host; (2) its morphology is immature and functional; (3) it has obvious invasiveness and metastasis. . Theoretically, the tumor cells proliferate exponentially. From a tumor cell to a 1 cm to 3 size, about 1 gram of tumor mass, ie 10 to 9 cells, it takes 30 generations to multiply and then increase. About 1 kg of tumor mass, ie 10~12