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肿瘤组织可有淋巴细胞和巨噬细胞浸润,这一现象提示宿主有免疫性抗肿瘤机制存在。业已明确,淋巴细胞具有多种抗肿瘤作用。T淋巴细胞和淋巴样天然杀伤(NK)细胞的作用被认为与肿瘤免疫监视有关。以往,有关的研究集中于淋巴细胞对非自体肿瘤的细胞毒作用;恶性肿瘤患者,非肿瘤患者和健康的正常人淋巴细胞对肿瘤组织的细胞溶解作用未见任何区别。其反应形式与NK细胞所引起者一致;后者的细胞溶解作用与组织相容性或提供者过去的免疫情况无明显关系。动物实
Tumor tissue may have infiltration of lymphocytes and macrophages, this phenomenon suggests that the host has an immune anti-tumor mechanism. It is clear that lymphocytes have a variety of anti-tumor effects. The role of T lymphocyte and lymphoid natural killer (NK) cells is believed to be related to tumor immune surveillance. In the past, related research focused on the cytotoxic effects of lymphocytes on non-autologous tumors; there was no difference in the cytolytic effects of lymphocytes on tumor tissues in patients with malignant tumors, non-tumor patients and healthy normal individuals. The response pattern is consistent with that caused by NK cells; the cytolysis of the latter is not significantly related to histological compatibility or the provider’s past immune status. Animal reality