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目的探讨硝呋太尔阴道片与制霉菌素栓在治疗妊娠期霉菌性阴道炎的临床疗效。方法收集2009年4月份-2012年4月份曾用药治疗的妊娠期霉菌性阴道炎患者92例,其中48例为硝呋太尔阴道片局部用药者,作为治疗组;其中44例为制霉菌素栓局部用药治疗者,作为对照组,观察2组用药临床疗效、不良反应、复发情况。结果治疗组治愈率为87.5%,对照组痊愈率为52.27%,治疗组明显高于对照组,差异有统计学意义(P<0.05)。结论硝呋太尔阴道片治疗妊娠期间霉菌性阴道炎具有较高的痊愈率,较低的不良反应及复发率,相比制霉菌素栓使用安全、方便、可靠。
Objective To investigate the clinical efficacy of nifuratel vaginal tablets and nystatin suppository in the treatment of mycotic vaginitis during pregnancy. Methods Ninety-two patients with mycotic vaginitis who had been treated during April 2009-April 2012 were enrolled, of whom 48 were nifuratel topical vaginal tablets as the treatment group, of which 44 were nystatin Topical drug treatment, as a control group, observed two groups of clinical efficacy, adverse reactions, recurrence. Results The cure rate of the treatment group was 87.5%, the cure rate of the control group was 52.27%, the treatment group was significantly higher than the control group, the difference was statistically significant (P <0.05). Conclusion Nifuratel vaginal tablets during pregnancy mycotic vaginitis has a higher cure rate, lower adverse reactions and recurrence rate, compared with the use of nystatin suppositories safe, convenient and reliable.