子宫颈癌术后放疗120例远期疗效分析

来源 :中华放射肿瘤学杂志 | 被引量 : 0次 | 上传用户:wangchongzhan
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目的分析子宫颈癌术后放疗及各项因素与远期疗效的关系,并与单纯放疗、单纯手术及术前放疗的疗效作对比分析。材料与方法1985年至1993年对120例宫颈癌进行了术后放疗,其中Ⅰ期23例,Ⅱ期97例。鳞癌112例,腺癌8例,均为浸润深肌层。盆腔有淋巴转移30例。放疗采用60Co全盆外照射,肿瘤量41~59Gy106例占88.3%。结果生存5年以上者99例,5年生存率为82.5%。年龄、期别、肿瘤大小、病理类型、手术方式与远期疗效无明显相关。有、无淋巴转移的5年生存率分别为63.3%和88.9%(P<0.01)。放疗剂量为41~59Gy组的5年生存率明显高于大于或小于该剂量组,分别为91.6%和57.1%(P<0.05)。结论本组术后放疗与文献中单纯放疗、单纯手术的远期疗效进行比较显示:Ⅰ期、Ⅱa期病例无差异,Ⅱb期单纯放疗为好。术中或术后发现病期较晚者补充放疗是必要的 Objective To analyze the relationship between the postoperative radiotherapy of cervical cancer and various factors and the long-term curative effect, and to compare with the curative effect of radiotherapy alone, simple surgery and preoperative radiotherapy. Materials and Methods Between 1985 and 1993, 120 cases of cervical cancer were treated with postoperative radiotherapy, of which 23 cases were stage Ⅰ and 97 cases were stage Ⅱ. 112 cases of squamous cell carcinoma, 8 cases of adenocarcinoma, all of which are deep myometrial infiltration. Pelvic lymphatic metastasis in 30 cases. Radiotherapy using 60Co full basin external irradiation, tumor volume 41 ~ 59Gy106 cases accounted for 88.3%. Results 99 patients survived more than 5 years, 5-year survival rate was 82.5%. Age, stage, tumor size, pathological types, surgical methods and long-term efficacy no significant correlation. The 5-year survival rates with and without lymphatic metastasis were 63.3% and 88.9%, respectively (P <0.01). The 5-year survival rates of patients treated with radiotherapy at 41-59 Gy were significantly higher than those of patients treated with radiotherapy at doses of 91.6% and 57.1%, respectively (P <0.05). Conclusions This group of postoperative radiotherapy and literature radiotherapy alone, simple surgery compared the long-term efficacy: stage Ⅰ, Ⅱ a case no difference, Ⅱ b period of radiotherapy alone is better. Radiotherapy is necessary during or after surgery to detect later stages of disease
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