肾细胞癌是一组遗传上、生化上、生物学和形态上异质性的肿瘤。尽管WHO肾肿瘤分类系统将Bellini集合管癌作为肾细胞癌的亚型,但是,由于缺少分子和生化研究的有力支持,Bellini集合管癌仍是有争议的疾病单元。最初,集合管癌分为高级别和低级别肿瘤,肾髓质癌被认为是高级别集合管 Renal cell carcinoma is a group of tumors that are genetically, biochemically, biologically and morphologically heterogeneous. Although the WHO Kidney tumor classification system uses Bellini ductal carcinoma as a subset of renal cell carcinoma, Bellini ductal carcinoma remains a controversial disease unit due to the lack of strong support for molecular and biochemical studies. Initially, tubal cancer was divided into high-grade and low-grade tumors, and medullary carcinomas were considered as high-grade collection tubes