裸鼠是先天性胸腺缺陷动物 ,T细胞缺乏 ,是现今进行人癌异种移植的理想动物。然而由于裸鼠的饲养条件要求较高 ,使其应用受到了很多的限制。我们教研室经过几年的探索 ,在无菌实验室内使用层流柜 ,再加上比较严格的管理制度 ,成功地饲养裸鼠 18批次 ,5 6 0余只 ,都顺利地完成了实验。所以 ,在实验室条件下使用层流柜短期饲养裸鼠是可行的 Nude mice are congenital thymus deficient animals, lack of T cells, is ideal for today’s human cancer xenotransplantation. However, due to the higher nursery feeding conditions, its application has been a lot of restrictions. After several years of exploration in our teaching and research laboratory, we used the laminar flow cabinet in aseptic laboratories, coupled with a more stringent management system, successfully nurtured 18 batches of nude mice and more than 5600 nurses, and successfully completed the experiment. Therefore, the use of laminar flow cabinet under laboratory conditions nursery short-term feeding is feasible