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亚急性坏死性淋巴结炎是一种原因不明的淋巴结亚急性坏死性病患,受累淋巴结有淋巴组织坏死和组织细胞增生,而没有粒细胞浸润。该病由Kikuchi′s于1972年首次报告。我院儿科在1984年12月至1990年1月共确诊9例。现报告如下。一般资料:9例病人中男4例,女5例。年龄9～14岁,平均11.5岁。春季发病3例,秋季2例,冬季4例。主要症状与体征:发热9/9,体温在38～42℃之间,热程由16～45天不等,大多数在应用肾上腺皮质激素后方退热。淋巴结肿大9/9(左颈5、右颈2、双颈1、左耳后2、腋下4、腹股沟4),肿大程度为1.0×1.0cm不等,肿大的淋巴结有触痛8/9。食欲不振5例,呕吐3例。有肝脾肿大者2例,1例为肝大肋下3cm和脾下1.5cm,另1例仅肝肋下1cm。
Subacute necrotizing lymphadenitis is an unknown cause of subacute necrotic lymph nodes, lymph nodes involved lymphoid tissue necrosis and histiocytosis, and no infiltration of granulocytes. The disease was first reported by Kikuchi’s in 1972. Pediatrics in our hospital in December 1984 to January 1990 were diagnosed in 9 cases. The report is as follows. General information: 9 patients in 4 males and 5 females. Aged 9 to 14 years old, with an average of 11.5 years old. Three cases occurred in spring, two in autumn and four in winter. The main symptoms and signs: fever 9/9, body temperature between 38 ~ 42 ℃, the heat range from 16 to 45 days, most of the application of adrenal hormone rear fever. Lymphadenopathy 9/9 (left neck 5, right neck 2, double neck 1, left ear 2, axillary 4, groin 4), swelling of 1.0 × 1.0cm range, swelling of the lymph nodes tenderness 8/9. 5 cases of loss of appetite, vomiting in 3 cases. There are 2 cases of hepatosplenomegaly, 1 case of large ribs 3cm and spleen 1.5cm, and the other 1 cases only rib 1cm.